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Muscle Pain Management: What Helps Beyond Painkillers?

Managing muscle pain starts with understanding what causes it. While painkillers may provide temporary relief, other approaches, such as adjusting daily activities, using heat or cold therapy, gentle movement, exercise and physiotherapy, may also help relieve discomfort and improve movement. The most suitable approach depends on the cause and severity of the pain. Muscle pain that is severe, persistent or unexplained should be assessed by a healthcare professional. [1, 2]
Have you ever woken up with sore muscles after exercising, experienced stiff shoulders after a long day at work, or felt an aching back after lifting something heavy?
Muscle pain, also known as myalgia, is a common complaint that can feel like aching, soreness, tightness, tenderness or cramping. It may affect one muscle or several muscle groups and can result from everyday activities, injuries or certain health conditions. [1]
While painkillers may help relieve discomfort, they are not the only approach to managing muscle pain. Depending on the cause, gentle movement, appropriate exercise, physiotherapy and changes to daily habits may also help. [1, 2]
So, when should you rest, and when is it better to keep moving? Should you reach for an ice pack or a warm compress? And can treatments such as TENS really help?
Let's explore the different ways to manage muscle pain safely and effectively.
What causes muscle pain?
Muscle pain can occur for many reasons, ranging from everyday activities to certain health conditions. Some common causes include: [1]
- Overuse or unfamiliar physical activity: Exercising more intensely than usual or performing repetitive movements can leave muscles feeling sore.
- Muscle strains or injuries: Overstretching or tearing muscle fibres can cause pain, tenderness and sometimes swelling.
- Prolonged sitting or repetitive movements: Staying in the same position for long periods or repeatedly using certain muscles may contribute to discomfort.
- Stress-related muscle tension: Emotional stress can cause muscles to tighten, particularly around the neck and shoulders.
- Certain illnesses or health conditions: Viral infections, such as influenza, and conditions such as fibromyalgia may cause muscle aches.
- Changes in body salts (electrolytes) or certain medicines: Abnormal levels of electrolytes, such as potassium or calcium, and side effects from some medicines can contribute to muscle pain.
Some medicines may cause muscle aches as a side effect. If you notice new or worsening muscle pain after starting a medicine or changing its dose, speak with a pharmacist or doctor. Do not stop or adjust prescribed medicines without professional advice. [1] However, seek urgent medical attention if muscle pain is accompanied by severe weakness or dark-coloured urine. [3]
What are the different ways to manage muscle pain?
There is no single approach that works for every type of muscle pain. The most suitable option depends on the cause, severity and duration of the pain, as well as your overall health.
For mild muscle aches, simple measures such as adjusting daily activities, gentle movement or heat and cold therapy may help. Other situations may require medicines, physiotherapy or further medical assessment.
Muscle pain management at a glance
| Approach | How it may help | Key point |
|---|---|---|
| Medicines | Oral or topical medicines may help relieve pain. Some medicines also reduce inflammation. [2, 4] | The most suitable option depends on the cause of pain, medical history and other medicines being taken. |
| Adjusting daily activities | Temporarily reducing activities that worsen the pain may help the affected muscles recover. [1] | Avoid complete inactivity for prolonged periods unless advised by a healthcare professional. |
| Heat or cold therapy | Cold may help relieve pain after a recent injury, particularly when swelling is present, while heat may soothe stiff or tight muscles. [1, 2, 5] | The most suitable option depends on the cause and timing of the pain. |
| Gentle movement and exercise | Gentle movement may help reduce stiffness, while gradual exercise can improve muscle strength and mobility. [1, 2] | Start slowly and avoid movements that cause sharp or severe pain, especially after an injury. |
| Physiotherapy | A physiotherapist can assess movement and recommend suitable exercises to improve strength, flexibility and mobility. [1, 2] | May be helpful when pain keeps returning, lasts longer than expected or affects daily activities. |
| Massage/manual therapy | May help relieve muscle tension and provide temporary pain relief for some people. [2, 4] | Benefits vary, and massage does not treat every underlying cause of muscle pain. |
| TENS (electrical nerve stimulation) | Uses mild electrical impulses that may provide temporary pain relief for some people. [4, 6] | It does not treat the underlying cause and may not be suitable for everyone. |
Which medicines may help muscle pain?
Pain-relief medicines may help manage muscle discomfort, depending on its cause and severity. These include oral medicines, such as tablets or capsules, and topical medicines, such as gels or creams applied to the affected area.
Common options include paracetamol, which helps relieve pain, and non-steroidal anti-inflammatory drugs (NSAIDs), which can reduce both pain and inflammation. [7, 8]
For adults with recent muscle, ligament or other soft-tissue injuries (excluding lower back injuries), clinical guidelines recommend topical NSAIDs, such as anti-inflammatory gels, as a first-line treatment when appropriate. Oral NSAIDs or paracetamol may also be considered, depending on the individual's needs and medical history. [4]
However, not every medicine is suitable for everyone. Factors such as existing health conditions, allergies, pregnancy and other medicines being taken should be considered before choosing a pain-relief option. [7, 8]
Taking a higher dose or combining different painkillers does not necessarily provide better pain relief and may increase the risk of side effects. [7, 8]
If you are unsure which medicine is suitable, speak with a pharmacist or doctor before increasing the dose or combining pain-relief products.
What non-drug approaches can help?
Medicines are not the only way to manage muscle pain. Depending on the cause, simple changes to daily activities and self-care habits may help relieve discomfort and support recovery. Some approaches that may help include: [1, 2, 5]
- Adjust your activities: Temporarily reduce activities that worsen the pain, while avoiding unnecessary prolonged rest.
- Try heat or cold therapy: Choose the approach that suits the type and timing of your muscle pain.
- Keep moving gently: Resume comfortable movements as tolerated. Avoid forceful stretching, particularly after a recent injury.
- Return to exercise gradually: Increase activity and strength-building exercises progressively rather than returning to strenuous activities too quickly.
- Consider physiotherapy: A physiotherapist can assess your condition and recommend suitable exercises, particularly if pain keeps returning or affects daily activities.
- Improve your working habits: Adjust your workstation, change positions regularly and take movement breaks when sitting or standing for long periods.
- Prioritise sleep and stress management: Adequate sleep and relaxation techniques may help support pain management, particularly when stress contributes to muscle tension.
Should you use heat or cold for muscle pain?
Both heat and cold therapy may help relieve muscle discomfort, but the most suitable choice depends on the cause and timing of the pain. [1, 5]
Cold therapy may help relieve pain following a recent muscle strain or injury, particularly when swelling is present. [5]
Heat therapy may help soothe tight or stiff muscles and improve comfort, especially when there is no significant swelling. [1]
Whichever method you choose, protect your skin by wrapping the hot or cold pack in a towel. Avoid applying extreme temperatures directly to the skin and limit each application to a short period, following the product instructions. Stop if you experience skin irritation, burning or unusual discomfort. [1, 5]
If you have reduced skin sensation, poor circulation or certain medical conditions, seek professional advice before using heat or cold therapy. [1, 5]
Can stretching and exercise help muscle pain?
In many cases, gentle movement and appropriate exercise can help reduce stiffness, maintain muscle strength and improve mobility. [1, 2]
However, the right type of activity depends on the cause of the pain. For example, gentle movement may be helpful for muscle soreness after exercise, while a recent muscle strain may require temporary activity modification before gradually returning to normal movement. [1, 5]
Stretching should be gentle and should not cause sharp or worsening pain. If you are unsure which exercises are suitable, a physiotherapist can recommend a programme based on your condition and physical abilities. [1, 5]
For people with persistent or recurring muscle pain, appropriate exercise and physiotherapy may form part of a broader pain management plan. The type and intensity of activity should be tailored to the underlying condition, physical abilities and individual goals. [2]
Start with gentle, comfortable movements and increase your activity gradually as symptoms improve. Avoid pushing through sharp or severe pain. If you experience significant swelling, new muscle weakness or severe pain following an injury, seek medical advice before returning to strenuous exercise. [1, 5]
What is TENS, and does it work?
TENS (transcutaneous electrical nerve stimulation) is a method of pain relief that uses a small device to send mild electrical impulses through pads placed on the skin near the painful area. These impulses produce a tingling sensation and may help reduce pain temporarily. The intensity can be adjusted to a comfortable level and should not be painful. [6]
A large systematic review involving 381 clinical trials found that TENS may help reduce pain during or immediately after treatment compared with placebo (a treatment that looks or feels similar but does not deliver the active treatment) in the relevant studies. However, the research included different types of pain, not just muscle pain. Its effectiveness may therefore vary depending on the condition and individual response. TENS may be considered an option for temporary pain relief in some situations, but it does not treat the underlying cause of muscle pain. [9]
Is TENS safe for everyone?
TENS is not suitable for everyone. People with pacemakers or other implanted electronic medical devices should not use TENS unless its safety has been confirmed by the appropriate healthcare professional. People with epilepsy and those who are pregnant should also seek professional advice before considering TENS. [6]
Electrode pads should not be placed on broken, infected, irritated or numb skin, over the front or sides of the neck, or on the chest and back at the same time. [6]
If you are unsure whether TENS is suitable for you, consult a healthcare professional before use.
Why does long-term painkiller use require care?
Painkillers can be helpful when used appropriately, but taking them regularly or for prolonged periods may increase the risk of side effects. [7, 8]
For example, non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may cause stomach irritation, ulcers or bleeding. They can also affect kidney function and increase cardiovascular risks in some people, particularly when taken at higher doses or for longer periods. [7, 8, 10]
Paracetamol is generally well tolerated when taken as directed, but exceeding the recommended dose can cause serious liver damage. [7]
Different painkillers carry different risks. It is therefore important to follow the recommended dosage and avoid combining pain-relief medicines without checking with a pharmacist or doctor. [7, 8]
If you find yourself needing painkillers frequently, or if the pain keeps returning despite treatment, speak with a pharmacist or doctor. Persistent or recurring muscle pain may have an underlying cause that requires further assessment. Managing the cause, where possible, is just as important as relieving the discomfort. [1]
Why combine medication with non-drug approaches?
Medicines and non-drug approaches can complement each other in managing muscle pain. While medicines may relieve discomfort, suitable exercise, physiotherapy and changes to daily habits may help improve movement and daily function. The most appropriate combination depends on the underlying cause and individual needs. [2]
When should you seek medical help for muscle pain?
Many mild muscle aches improve with simple self-care. However, some symptoms may indicate an underlying problem that requires medical assessment.
Speak with a healthcare professional if:
- Muscle pain persists longer than expected, keeps returning or gradually worsens.
- The pain is unexplained or does not improve with appropriate self-care.
- The affected area becomes swollen, red, warm or increasingly tender.
- Muscle pain begins after starting a new medicine or changing its dose.
- The pain interferes with your sleep, movement or daily activities.
Seeking medical advice can help identify the possible cause and determine whether further assessment or treatment is needed. [1]
When is muscle pain an emergency?
Although most muscle aches are not serious, certain symptoms may indicate a condition requiring immediate medical attention.
- Severe muscle pain or weakness accompanied by dark or cola-coloured urine, which may be a sign of rhabdomyolysis. [3]
- Sudden, severe or rapidly worsening muscle pain after an injury, particularly when the affected area becomes very swollen, tight or extremely painful. [11]
These symptoms may indicate a serious condition that requires immediate medical assessment.
In a medical emergency, seek care at the nearest emergency department or call 999 in Malaysia.
Speak with a CARiNG pharmacist
If you are unsure which pain-relief option is suitable, speak with a pharmacist or doctor. A CARiNG pharmacist can provide advice on the appropriate use of medicines, check for potential medicine interactions and help identify when further medical assessment may be necessary. Persistent, severe or unexplained muscle pain should be assessed by a doctor.
Find your nearest CARiNG Pharmacy →Useful resources
- Ministry of Health Malaysia – Pain Management Handbook – Malaysian guidance on different approaches to pain management, including self-care, physiotherapy and TENS.
- MedlinePlus – Muscle aches – Overview of common causes, home care and warning signs for muscle pain.
- CDC – Nonopioid therapies for pain management – Evidence-based overview of nonopioid medicines and non-drug approaches to pain.
- NHS – TENS – Practical guidance on how TENS works and who should take extra care.
- NHS – Sprains and strains – Self-care guidance for common muscle and ligament injuries.
Medical disclaimer: This article is intended for general health education and does not replace professional medical advice, diagnosis or treatment.
Muscle pain can have many possible causes, and the appropriate management depends on the individual's condition. Seek medical advice if pain is severe, persistent, unexplained or accompanied by concerning symptoms.
Consult a pharmacist or doctor before using pain-relief medicines if you have existing medical conditions, take other medicines, are pregnant or are unsure which treatment is suitable.
Frequently asked questions about muscle pain management
What is muscle pain?
Muscle pain, also known as myalgia, may feel like aching, soreness, tightness or cramping. It commonly occurs after physical activity, muscle overuse or injury. However, certain illnesses, health conditions and medicines may also cause muscle pain. [1]
Should I use heat or ice for muscle pain?
Can stretching help muscle pain?
Gentle stretching may help reduce muscle stiffness, depending on the cause of the pain. However, stretching too soon after an injury may worsen discomfort. Start with comfortable movements and avoid forcing a stretch. If pain persists or keeps returning, consider seeking advice from a physiotherapist. [1, 5]
Can TENS help relieve muscle pain?
When should I see a doctor for muscle pain?
Mild muscle soreness after exercise often improves within a few days. However, seek medical advice if the pain is severe, unexplained, worsening or keeps returning. You should also seek assessment if it is accompanied by unusual swelling, redness, muscle weakness or other concerning symptoms. [1]
Are painkillers safe to take every day?
The safety of regular painkiller use depends on the medicine, dosage, duration and your health condition. For example, prolonged use of oral NSAIDs may increase the risk of stomach bleeding, kidney problems and cardiovascular complications. If you need painkillers frequently, consult a pharmacist or doctor to review your treatment. [7, 8, 10]
Can medicines cause muscle pain?
Yes. Certain medicines may cause muscle pain as a side effect. If you develop new or worsening muscle aches after starting a medicine or changing its dose, consult a pharmacist or doctor. Do not stop or adjust prescribed medicines without professional advice. [1]
Should I rest or keep moving when I have muscle pain?
It depends on the cause. For mild muscle soreness, gentle movement may help reduce stiffness and maintain mobility. However, a recent injury may require temporarily avoiding activities that worsen the pain. As symptoms improve, gradually return to your usual activities without pushing through severe pain. [1, 5]
View references 11 sources
- MedlinePlus. Muscle aches. Bethesda (MD): National Library of Medicine (US) [cited 2026 Oct 17]. Source
- Centers for Disease Control and Prevention. Nonopioid therapies for pain management. Atlanta (GA): CDC [cited 2026 Oct 17]. Source
- Centers for Disease Control and Prevention. Signs and symptoms of rhabdomyolysis. Atlanta (GA): CDC; 2025 Jan 14 [cited 2026 Oct 17]. Source
- Qaseem A, McLean RM, O'Gurek D, et al. Nonpharmacologic and pharmacologic management of acute pain from non-low back, musculoskeletal injuries in adults: a clinical guideline from the American College of Physicians and American Academy of Family Physicians. Ann Intern Med. 2020;173(9):739-748. doi:10.7326/M19-3602. Source
- National Health Service. Sprains and strains. London: NHS [cited 2026 Oct 17]. Source
- National Health Service. TENS (transcutaneous electrical nerve stimulation). London: NHS [cited 2026 Oct 17]. Source
- MedlinePlus. Over-the-counter pain relievers. Bethesda (MD): National Library of Medicine (US) [cited 2026 Oct 17]. Source
- National Health Service. NSAIDs. London: NHS [cited 2026 Oct 17]. Source
- Johnson MI, Paley CA, Jones G, Mulvey MR, Wittkopf PG. Efficacy and safety of transcutaneous electrical nerve stimulation for acute and chronic pain in adults: a systematic review and meta-analysis of 381 studies – the meta-TENS study. BMJ Open. 2022;12(2):e051073. doi:10.1136/bmjopen-2021-051073. Source
- Medicines and Healthcare products Regulatory Agency. Non-steroidal anti-inflammatory drugs (NSAIDs): cardiovascular risks. London: MHRA; 2014 Dec 11 [cited 2026 Oct 17]. Source
- National Health Service. Compartment syndrome. London: NHS [cited 2026 Oct 17]. Source
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